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Is still the most lethal gynecologic malignancy worldwide. Although most ovarian carcinoma cells are initially sensitive to chemotherapy, there is always a small population cells that always survives and initiates new tumors which causes recurrence [31]. The verification of tumor heterogeneity further enhances the hypothesis of CSCs. Compelling evidence has shown that ovarian carcinomas with enric
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Arian CSCs include CD44, epithelial cell adhesion moleculeHuang et al. BMC Cancer (2015) 15:Page 6 ofTable 3 The associations of ALDH1 expression levels in stromal cells and the clinical and pathologic characteristicsALDH1 IHC score in stromal cells 1 (negative) Number Age (years old): 39 40?9 50?9 60?9 70 missing Histological subtype: Serous carcinoma Mucinous carcinoma Endometrioid carcinoma Cle
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Etc. [34, 35]. However, it still remains challenging to identify one single marker or several combined markers to specifically identify all the CSCs in ovarian tumor, and the exact roles of these `stemness' related markers, are still poorly understood due to either a current lack of understanding of the biological functions of the markers, or frequently the lack of information correlating the vari
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(35.7 ) 4 (22.2 ) 15 (12.8 ) 10 (12.7 ) 0.032 163 18 19 11 11 5 21 67 (41.1 ) 4 (22.2 ) 4 (21.1 ) 6 (54.5 ) 2 (18.2 ) 3 (60.0 ) 80 (49.1 ) 3 (16.7 ) 9 (47.4 ) 4 (36.4 ) 6 (54.5 ) 1 (20.0 ) 16 (9.8 ) 11 (61.1 ) 6 (31.6 ) 1 (9.1 ) 3 (27.3 ) 1 (20.0 )
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Arian CSCs include CD44, epithelial cell adhesion moleculeHuang et al. BMC Cancer (2015) 15:Page 6 ofTable 3 The associations of ALDH1 expression levels in stromal cells and the clinical and pathologic characteristicsALDH1 IHC score in stromal cells 1 (negative) Number Age (years old): 39 40?9 50?9 60?9 70 missing Histological subtype: Serous carcinoma Mucinous carcinoma Endometrioid carcinoma Cle
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Arian CSCs include CD44, epithelial cell adhesion moleculeHuang et al. BMC Cancer (2015) 15:Page 6 ofTable 3 The associations of ALDH1 expression levels in stromal cells and the clinical and pathologic characteristicsALDH1 IHC score in stromal cells 1 (negative) Number Age (years old): 39 40?9 50?9 60?9 70 missing Histological subtype: Serous carcinoma Mucinous carcinoma Endometrioid carcinoma Cle
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Arian CSCs include CD44, epithelial cell adhesion moleculeHuang et al. BMC Cancer (2015) 15:Page 6 ofTable 3 The associations of ALDH1 expression levels in stromal cells and the clinical and pathologic characteristicsALDH1 IHC score in stromal cells 1 (negative) Number Age (years old): 39 40?9 50?9 60?9 70 missing Histological subtype: Serous carcinoma Mucinous carcinoma Endometrioid carcinoma Cle
1
Etc. [34, 35]. However, it still remains challenging to identify one single marker or several combined markers to specifically identify all the CSCs in ovarian tumor, and the exact roles of these `stemness' related markers, are still poorly understood due to either a current lack of understanding of the biological functions of the markers, or frequently the lack of information correlating the vari